While most forms of magnesium can help support sleep by calming the nervous system and relaxing muscles, magnesium bisglycinate is widely considered the best magnesium for sleep. It combines magnesium—which plays a key role in melatonin regulation and stress reduction—with glycine, an amino acid naturally bonded to magnesium that promotes relaxation and deeper, more restorative sleep.

PrizMAG Pure Magnesium Bisglycinate stands out because it contains just one ingredient: magnesium bisglycinate. It’s one of the only magnesium supplements on the market that is 100% pure, with no fillers, binders, stearates, or manufacturing agents—making it a clean, effective, and trustworthy choice.

Plus, it's gentle on the digestive tract, making it ideal for sensitive individuals. With four industry awards—including Best Sleep Product and Best Stress Relief Product—PrizMAG is a science-backed solution for better sleep and reduced stress.

To ensure optimal absorption by the body, magnesium needs to be bound to specific carriers, a principle applicable to all minerals. Magnesium citrate pairs magnesium with citric acid, magnesium glycinate (or bisglycinate) with the amino acid glycine, magnesium malate with malic acid, and magnesium oxide is a salt combining magnesium and oxygen. This diversity leads to the belief that certain magnesium forms are more effective for specific health conditions. For instance, magnesium malate, with its malic acid content, is often considered beneficial for energy, making it a preferred choice for those with chronic fatigue syndrome. Similarly, magnesium bisglycinate, bound to glycine, is favored for sleep and relaxation due to glycine's positive impact observed in sleep studies. While the association between magnesium forms and health conditions holds merit, it's crucial to recognize that different magnesium types are absorbed at varying rates. Optimal benefits can only be achieved when the body efficiently absorbs magnesium.

Because only 1% of your body's magnesium is present in your blood, relying solely on blood tests may not provide an accurate reflection of your overall magnesium levels. If a blood test indicates low magnesium, it could imply a dangerously low level. We advocate assessing your magnesium needs based on your symptoms. Magnesium expert Dr. Carolyn Dean, MD suggests that over 80% of the population may be deficient in magnesium. If you're concerned about your magnesium levels and prefer confirmation through testing, consider consulting with your naturopathic doctor or holistic nutritionist for a hair analysis, which can offer insights into the mineral levels in your body.

Bathing in Epsom salts (magnesium sulfate) can offer some magnesium absorption through the skin, but it’s typically not enough to correct a deficiency. Most people don’t soak long enough for meaningful absorption, and magnesium sulfate is not as easily absorbed as other forms.

For more effective topical magnesium absorption, consider switching to SeaMAG magnesium chloride flakes. Magnesium chloride is better absorbed through the skin than Epsom salts and is often recommended for those looking to increase magnesium levels transdermally.

While magnesium baths can be a great addition to your wellness routine, they should be used as a supplemental source of magnesium—not your only one. For best results, combine topical magnesium with a high-quality oral supplement to fully support your magnesium needs.

While it’s possible to meet your magnesium needs through diet, it requires deliberate effort. Over the past few decades, magnesium levels in soil have declined significantly, reducing the mineral content of even whole foods. Meanwhile, processed and fast foods are typically low in magnesium, making them poor dietary sources.

Magnesium is also water-soluble, meaning it can leach out of food during cooking — especially when boiling vegetables. Eating raw foods may help preserve magnesium content, but there’s a catch: many magnesium-rich foods (like spinach, nuts, and seeds) are also high in oxalates. Oxalates can bind to magnesium in the digestive tract, reducing absorption and carrying it out of the body. (For more on this, read our article: “Magnesium Deficiency and the Role of Oxalates”.)

Magnesium supports hundreds of essential enzyme-driven processes, from energy production to muscle function. If you suspect your intake is low, consider tracking your food choices and supplementing if needed — especially if you follow a modern diet or cook most of your meals.

The response depends on the specific medication you're taking. If you're on prescribed medications, it's important to consult with your pharmacist to determine which supplements are safe to take alongside your current prescriptions.

Yes—taking more than one form of magnesium supplement is not only safe, it can be more effective. While all magnesium supports hundreds of vital processes in the body, the form it's bound to—also known as the carrier—can influence how well it’s absorbed and where it may be most effective.

For example, MAG3N8 contains magnesium L-threonate, a form that many customers report helps with mental clarity and cognitive function, especially when taken in the morning. Because magnesium L-threonate has a lower elemental magnesium content, it’s often paired with a higher-yield option to support the body’s broader magnesium needs—like PrizMAG Pure Magnesium Bisglycinate.

We also have many customers who take MAG365 BF in the morning—an ionic magnesium citrate powder with added vitamins and minerals, ideal for daily use to support energy, muscle recovery, and the body’s stress response. In the evening, PrizMAG, made with pure magnesium bisglycinate, is a popular choice to help relax the nervous system and promote deeper, more restful sleep.

For best results, consider:

• MAG3N8 or MAG365 BF in the morning
• PrizMAG in the evening
• and adjusting your dosage of each based on your individual needs.

Splitting your intake can also enhance magnesium absorption and help maintain steady levels throughout the day.

Magnesium plays a crucial role in regulating blood pressure. A recent study found that magnesium supplementation can lower blood pressure by promoting the relaxation of blood vessels and preventing constriction, thereby enhancing overall blood flow. Additionally, studies suggest magnesium supplementation may be effective in reducing high blood pressure among individuals dealing with insulin resistance, prediabetes, and other chronic conditions commonly associated with cardiovascular disease.

Please read our article “Which Form of Magnesium is Best?”.

Absolutely. Magnesium is a naturally occurring mineral present in food, and it is deemed safe for pregnancy. For additional details, please refer to our FAQ titled "Is MAG365 safe for pregnancy?" under the MAG365 FAQ page.

Magnesium absorption primarily occurs in the small intestine through a protein binding transport system and passive diffusion via the bulk flow of water. The overall state of health and dietary factors influence magnesium absorption. It's crucial to recognize that the presence of oxalates in certain foods can impact the absorption of dietary magnesium (refer to "Magnesium Deficiency and the Role of Oxalates" for more information). The absorption rate of magnesium from supplements varies, with forms that dissolve well in liquid, like magnesium citrate, being more absorbable than others. Magnesium deficiency may result from reduced magnesium absorption in the gut or increased magnesium excretion through urine. As age advances, the ability to absorb magnesium in the intestines tends to decrease, while urinary output of magnesium tends to increase. This underscores the effectiveness of ionic magnesium citrate, which boasts a 30-40% higher absorbability rate than any other form of magnesium.

The most prevalent symptoms of magnesium deficiency can include: Low energy, sleep problems, weakened bones, kidney stones, emotional disruption, heightened sensitivity, muscle pains and cramps, disruption of normal heart rhythms. For additional details, please refer to our article "Magnesium: Are You Getting Enough?"

Magnesium deficiency is prevalent for several reasons. Firstly, modern farming methods have led to a reduction in magnesium levels in our soil, resulting in a diminished magnesium content in our overall food supply. The widespread consumption of processed foods in the Western diet exacerbates the issue, as most magnesium is lost during food manufacturing. Moreover, magnesium plays a crucial role in over 80% of the body's functions, contributing to its high "burn rate." Various factors such as stress, exercise, extreme temperatures, prescription medications, alcohol consumption, trauma, and poor diet further accelerate the depletion of magnesium stores in the body. Each of these elements contributes to the rapid utilization of magnesium, leading to an increased risk of deficiency.

Magnesium oxide boasts the highest elemental magnesium content per weight, but its absorption is poor, with some studies indicating an absorption rate of only 4%, largely due to its insolubility in water. Forms of magnesium known to potentially cause diarrhea include magnesium carbonate, chloride, gluconate, and oxide. Magnesium citrate, a salt form of magnesium combined with citric acid, exhibits a notably high absorption rate and good solubility in water, making it easily mixable with liquids. Some research suggests that magnesium citrate, especially in ionic formulas like our MAG365, is among the most bioavailable forms, facilitating efficient absorption in the digestive tract. In contrast, non-ionic formulas have lower absorbability (refer to our article "Understanding Ionic"). Magnesium glycinate, or bisglycinate, demonstrates a very high absorption rate with a milder laxative effect compared to other forms. Its absorption in a different area of the intestine minimizes potential GI discomfort and enhances effectiveness. Formed from elemental magnesium and the amino acid glycine, magnesium glycinate is easily absorbed and is known for its calming properties. It may help alleviate anxiety, depression, stress, and insomnia. While promising, scientific evidence on magnesium glycinate's efficacy for these conditions is limited, necessitating further studies. For more comprehensive details, please refer to our article "Which Form of Magnesium is Best?"

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Magnesium helps to calm the muscles and nerves, but it does not make you drowsy.  Many people prefer to take it before bed, because the calming effect helps them to sleep more soundly. However, magnesium is also needed to make ATP, which is used by every cell in the body for energy, so it is fine to take at any time of day.  In fact, we recommend dividing your dose throughout the day, with an additional dose at night.

If you're looking for magnesium to help relieve constipation, magnesium citrate is one of the most effective forms. It works by drawing water into the intestines and relaxing the bowel muscles, which helps get things moving gently and naturally.

One standout option is MAG365 Ionic Magnesium Citrate, a highly absorbable powder that must be activated in warm water to create an ionic magnesium solution. This form is quickly absorbed by the body and starts working fast. It hydrates the bowel, relaxes intestinal muscles, and helps promote regular, comfortable elimination—without harsh laxatives or sudden urgency.

Unlike some harsher magnesium laxatives, MAG365 is ideal for daily use and gentle enough for those with sensitive digestive systems. Plus, it's a pleasant, drinkable form, making it an easy addition to your daily wellness routine—no pills required.